These drugs mimic the effects of the naturally occurring GLP-1 hormone, which is produced in the small intestine and plays a crucial role in regulating insulin secretion, glucose homeostasis, and appetite
The study established that four hour intravenous infusions of GLP-1 (7-36) completely normalised blood glucose levels of patients with type 2 diabetes admitted to hospital for insulin therapy (Nauck, Klein, rskov)
Successful therapeutic peptides in this category often show high selectivity for their target enzymes while maintaining appropriate pharmacokinetic properties for clinical use
Description Liposomal Glutathione L-glutathione in truly dry liposomes
Besides, GLP-1R agonists also regulated PC12 cells growth through regulating cAMP/PKA signaling pathway (212)
Chemistry, structure and function of approved oligonucleotide therapeutics