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Rodent MSC also exhibit ameliorated osteogenic differentiation when treated with GLP-1-RA, mirroring findings in human MSC
These limitations have driven enormous interest in natural compounds that might work along similar metabolic pathways -- not as drug replacements, but as part of a broader strategy for metabolic health
Johansson, C
Heterologous expression of an engineered bifunctional bacterial GSH biosynthetic enzyme (GshF) in mitochondria enables mitochondrial GSH production and ameliorates the metabolic and proliferative defects caused by its depletion
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