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In vitro studies on human mononuclear cells also showed that alogliptin (0.5, 1 and 5 nM) treatment for 24 h exhibited a decrease in TLR-4 mediated increase in IL-1 and IL-6 [55]
IJMS 21 (19), 7084
No psychological, physiological, or biochemical side effects were reported [20]
It is possible that children with lower baseline glutathione levels may need a higher dose or a longer intervention to attain similar behavioral outcomes
Yang and co-workers reported a nanomedicine composed of dendritic mesoporous silica nanoparticles (DMSNs), Fe 3 O 4 , Mn, and glutaminase inhibitor Telaglenastat (CB-839) (termed DFMC) for restored oxaliplatin chemosensitivity on the basis of the GSH-responsive and -exhausting effect (Figure 4C) (Wu et al., 2022
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