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Finally, we summarize recent advances in butyrate structural modification and pharmaceutical development, emphasizing the promising application of butyrate-related combination therapy

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Its postulated that its antimelanogenic properties result from a variety of mechanisms including stimulation of pheomelanin synthesis rather than darker eumelanin, its antioxidant effects, and interference with intracellular trafficking of melanin-causing enzymes

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Studies demonstrate that apigenin administration improves cognitive and memory deficits in TBI rodent models, as evidenced by enhanced performance in the Morris water maze and Step-down inhibitory avoidance tests (Guo et al., 2023)

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