Therefore, in this study, we have used human hepatoma HepG2 cancer cells, a commonly used cell culture model, which has been treated with buthionine sulfoximine (BSO), a GSH depleting agent and N-acetylcysteine (NAC), a precursor of GSH synthesis, to study the implications of altered glutathione metabolism in ASA-induced oxidative stress, redox homeostasis and mitochondrial dysfunctions
No data exists on developmental effects, and cell proliferating properties raise theoretical concerns
T., Anastasiou, D., Mullarky, E., Vokes, N
C., and Tseng, L
Improved gastrointestinal protection signaling
In contrast, during chronic or infected wound states, the pH shifts to alkaline levels (pH 79) as a result of microbial activity 53,54