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Excessive NO production interacts with ROS to generate peroxynitrite (ONOO ), a highly reactive nitrogen species capable of nitrating proteins and inactivating mitochondrial enzymes (Takatani et al., 2018
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(2023) 37:e23430
Secondly, resveratrol has also been demonstrated to attenuate MDR by targeting DNA damage, and concomitantly interfering with DNA repair and replication [223, 224]
When viewed through these four categories, it becomes clear why peptides are catching attention: they dont artificially enhance performance they protect it