Hydroxocobalamin has an excellent safety profile, as excess B12 is readily excreted in urine
Kimmel, A
Common Side Effects When side effects occurred, they were typically mild, transient, and similar in frequency to placebo groups: Reported Adverse Effects Most Common (occurring in small percentage of participants): Mild to moderate headaches (most frequently reported, often resolving with continued use) Injection site reactions (minor redness, swelling, or irritation at injection site) Gastrointestinal effects (particularly at higher oral doses: mild nausea, diarrhea, flatulence) Fatigue (reported occasionally during initial adaptation period) Rare Events: One case of chest tightness was deemed possibly related to treatment in safety trials
Conclusion Bacteriostatic water (BAC water) for injection is sterile water with 0.9% benzyl alcohol designed specifically for multi-dose dilution in research and compounding
So are B12 injections the answer to restoring health in those with low levels
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