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The stratum corneum has a passive transepidermal absorption ceiling that sits at roughly 500 daltons, which means anything smaller than that has a chance of getting through intact skin and anything larger does not 4
They are also beneficial for individuals with poor dietary intake of B12 (including vegetarians and vegans), older adults with reduced absorption, patients with digestive conditions like Crohns disease or celiac disease, and those managing conditions like anemia, sciatica, or peripheral neuropathy
Provencher SW
Note why you are considering MIC-B12, any relevant history around energy, methylation, or B12 status, and any other supplements or medications you take
Science 309 , 18291833 (2005)
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