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Efficacy and safety of canagliflozin as add-on therapy to a glucagon-like peptide-1 receptor agonist in Japanese patients with type 2 diabetes mellitus: a 52-week, open-label, phase IV study
Distinguishing between problematic pain and adaptive pain helps avoid unnecessary concern or premature discontinuation of therapy
The strength of our work is the prospective, double-blind, placebo-controlled trial design and the reasonably large cohort of patients with primary polydipsia
PNC
Maenner MJ, Warren Z, Williams AR, Amoakohene E, Bakian AV, Bilder DA, et al
Histological analysis showed that FOXO4-DRI treatment improved the testicular microenvironment, leading to thicker seminiferous epithelia, increased spermatogenic cells, and more mature spermatozoa in the central lumen
