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The quality-of-life improvements go beyond weight itself

None of the study participants had a history of metabolic syndrome at baseline

Most people notice changes in their own appearance by weeks 6-8, but friends and family typically comment unprompted around months 3-4

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In particular, the upregulation of IL6, IL1, and Stat3, along with alterations in immune cell populations such as MDSCs and regulatory T cells, and inflammasome suggest plausible mechanistic links to BC pathogenesis 137