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In a phase 2 randomised controlled trial published in the New England Journal of Medicine (Jastreboff et al., 2023), participants receiving the highest doses of retatrutide achieved a mean weight reduction of approximately 1724% of body weight over 48 weeks, depending on dose
Most studies report odds ratios above 10 in heterozygotes who are heavy drinkers
Huby and Gautier, 2022)
Combinada con entrenamiento de fuerza, favorece adems mayores ganancias de masa libre de grasa a medio plazo
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Findings remain heterogeneous across models and study sizes, so additional controlled human studies are encouraged (PMC)
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