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doi: 10.2174/1871525716666180118152158 139 PatelVJoharapurkarAKshirsagarSPatelMSutariyaBPatelHet al

They also ran flow cytometry (Annexin V/PI staining) and western blot analysis to measure specific survival and death markers: Bcl-2, Bax, caspase-3, and PARP

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It also activates lysyl oxidase (LOX), the copper-dependent enzyme responsible for collagen and elastin crosslinking in the extracellular matrix

These are classic red-flag symptoms of a cardiac event, and they require urgent evaluation

If something doesnt seem right, check in with a dermatologist