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They seem to be well tolerated in patients with mild and moderate liver function impairment, though they should be cautiously administered in patients with advanced liver disease.77,78 SGLT2 inhibitors Selective renal sodium glucose co-transporter 2 (SGLT2) inhibitors improve glycemic control in an insulin-independent fashion through inhibition of glucose reuptake in the kidney.79 The most used drugs from this group are: dapagliflozin, canaglifozin and empaglifozin
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Like the role of chronic alcohol consumption and an associated poor diet leading to thiamine deficiency, alcoholism is the leading cause of deficiency in B6
Ould-Brahim et al., 2018
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