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Cell Metab 17(6):819837 Athauda D, Foltynie T (2016) The glucagon-like peptide 1 (GLP) receptor as a therapeutic target in Parkinsons disease: mechanisms of action
The conversation covers how our understanding of obesity as a chronic, relapsing disease has changed over the past 30 years, what the new clinical versus preclinical obesity framework means for how we diagnose and treat it, how GLP-1 drugs work and why they've succeeded where earlier medications failed, what the STEP and SELECT trials revealed about the disease-modifying potential of semaglutide, and how patients and clinicians should be thinking about who these drugs are really for
placebo): Diarrhoea: 27.4% / 33.5% / 33.6% vs
In clinical trials, many people who took Semaglutide lost at least 5-10% of their body weight
Medical supervision improves safety and long-term success
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