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Thus, we followed patients from cohort entry until the outcome (detailed below), switching or discontinuation of study drug (defined as the lack of a prescription by the end of the 90 day grace period), death from any cause other than suicide, end of registration with the CPRD, or end of the study period (29 March 2021), whichever occurred first

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As dietary components, these polyols may play a significant role in modulating gut hormone secretion, which is crucial for appetite control and energy homeostasis