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It undergoes enzymatic processing from its preproglucagon peptide precursor within intestinal L-cells, ultimately giving rise to GLP-1(1-37) and peptide variants including GLP-1(7-36)

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Cotadutide, a GLP-1 and Gcg receptor dual agonist, in obese or overweight patients with type 2 diabetes: a randomised, controlled, double-blind, ascending dose and phase 2a study

10.3390/ijms22031458 40 RgnierM.Van HulM.KnaufC.CaniP

Mar 5 2024;465:133412