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In obese wild-type mice, chronic experimental exposure was associated with reduced body weight and body fat, increased lipolytic sensitivity, and increased beta-3-adrenergic-receptor RNA expression in adipose tissue

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The strongest published finding is from the foundational Biochemical Pharmacology study by Neelakantan et al.: in diet-induced obese mice, daily 5-Amino-1MQ administration produced reductions in body weight, white adipose tissue mass, and adipocyte size without any significant change in food intake