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They come with different side effects which might affect people in varying ways

But returning to side effects, we can see the 6mg and 10mg groups have side effect profiles comparable to other drugs weve looked at today and so in my mind those are both viable doses to trial in phase 3

They come with a host of other health benefits, too

Manufacturers calibrate the in-use window to keep hydrolysis below the threshold where potency drops more than 5%

Notably, pro-inflammatory genes such as Il13, Il5, Csf2 among others were consistently downregulated following melatonin treatment ( Figure 5C )

It has been used longer, so production and sourcing are more established