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Maintenance and discontinuation SURMOUNT-4, continue vs placebo switch after lead-in to about 20.9% loss: stopping regained about +14% over 52 weeks while continuing lost a further -5.5%
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They are amino acid chains that act as signaling molecules
Histological analysis further supported these behavioral findings, showing partial restoration of tyrosine hydroxylase staining in the substantia nigra of Dihexa-treated animals, indicative of neuronal protection and recovery [2]
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