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Individuals with personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2 should not use these medications

These systemic improvements translate directly to the liver, where GLP-1 RAs provide potent hepatic benefits that extend beyond simple weight loss (Summary of studies evaluating the role of GLP-1RAs in SLDs presented in Table 1)

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Thus, as far as mitochondrial oxidative stress homeostasis is concerned, mGSH is a vital factor maintaining mitochondrial function, controlling cell survival/death, and its depletion causes cell damage and facilitates cell death [57, 59]