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In vivo studies Experimental work Animals were maintained under specific-pathogen-free conditions and in compliance with the Northern Ireland Department of Health (under PPL 2874 and 2960) regulations with approval from the QUB Animal Welfare and Ethical Review Body

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Furthermore, the prebiotic intervention reshaped the HFD-induced imbalanced gut microbiota by modulating the composition of the bacterial community, markedly increasing Bacteroidetes