Collectively, Kang and colleagues reinforced the observation that cystine starvation could sensitize cancer cells to ferroptosis by inducing intracellular glutamate accumulation, and uncovered that GCLC potentially alleviates cellular ferroptotic stress by both mediating GSH synthesis and scavenging glutamate
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L.UdovicicM.SimonjiK.HanzevackiJ
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The second hormone in tirzepatide, glucose-dependent insulinotropic polypeptide (GIP), also impacts insulin production and slows digestion, thereby reducing hunger and improving blood sugar
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