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Both SPHKAP and AKAP11 harbour a FFAT (two phenylalanines in an acidic tract) motif 30,31 , a specific short protein sequence that binds to the Major Sperm Protein (MSP) domain of VAPs (Supplementary Fig
Aging models Given the close association between diabetes, aging, and neurodegeneration, GLP-1RAs have been tested in in vivo aging models
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In another study, both circulating DPP-4 levels and the amount released from adipocyte explants in vitro were found to be positively correlated with adipocyte size as well as with anthropometric parameters such as BMI, waist circumference and percent body fat (79)
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