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Establishment of K7M2-Luc orthotopic osteosarcoma mouse model and therapeutic effect evaluation Tumor model establishment To establish orthotopic model, K7M2 cells (3 10 6 cells/well) were dispersed in PBS buffer and implanted into right tibia of BALB/c mice
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Furthermore, a recent finding demonstrated that -synuclein released from injured dopaminergic neurons triggers activation of NF-B and release of pro-inflammatory cytokines with further aggravation of dopaminergic neurons in a positive-loop fashion (Dolatshahi et al
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If appropriate, a personalized protocol is prescribed based on individual needs
They found that all groups receiving GcgR agonists showed lower liver lipid content than the control group
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