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95% CI, 0.49 to 1.28) but also between patients receiving SGLT2i and GLP1-RA (OR, 0.66

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Weight reduction can improve IR, muscle energy balance, and muscle microcirculation by restoring glucose metabolism and oxidative phosphorylation and improving mitochondrial function

There are references to early-phase or investigator-initiated work in specific niches (such as inflammatory bowel conditions), but no robust, peer-reviewed, placebo-controlled human safety dataset has been widely published

So endurance work, unlike the Peloton or cycling that's really load bearing, although you're cycling really hard with the resistance