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Selective versus total insulin resistance: a pathogenic paradox
Even then, some uncommon risks may only become clearer after broader use, if a medicine is eventually approved
To advance personalized treatment strategies, it is critical to improve current understanding of the overlapping pathophysiology as well as the heterogeneity of obesity and diabetes, including their multi-hormonal dysregulation and inter-individual differences [24, 25]
Angold A, Costello EJ, Worthman CM
Designing a Dual GLP-1R/GIPR Agonist from Tirzepatide: Comparing Residues Between Tirzepatide, GLP-1, and GIP