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The underlying mechanism involves reactive oxygen species (ROS) generated by polyol pathways, advanced glycation end products, and reduced nicotinamide adenine dinucleotide phosphate oxidase, which damaged glomeruli and renal tubules directly, leading to proteinuria and fibrosis [93, 94]

Depression Major depressive disorder (MDD) affects 4.217% of populations worldwide, and is a common cause of disability

Reducing the risk of cardiac events: Research published in 2025 suggests that magnesium supplements can reduce the risk of heart failure and major cardiac events, such as heart attack and stroke, in people with diabetes

In this episode, McCall McPherson sits down with fertility expert Natalie Crawford to uncover the root causes behind infertilityfrom hormones and thyroid health to inflammation and lifestyleempowering you with the knowledge to take control of your reproductive health

10.1038/nrd.2018.109 3 ChenJ