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Understanding these mechanisms at a fundamental level can provide insights into the development of targeted therapeutic strategies

8.3 Manufacturing, formulation, and cost of goods From a commercial perspective, peptide therapeutics face persistent scrutiny regarding manufacturing complexity and cost of goods (Babu et al., 2021)

In addition, DNL was independently associated with intrahepatic triglyceride levels [39], and inadequate suppression of DNL during fasting could be a key feature in NAFLD patients [38, 39]

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doi: 10.1016/s2215-0366(23)00025-1 176 DunleavyCElsworthyRJUpthegroveRWoodSJAldredS