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Initially developed for diabetes, they are now widely used for obesity treatment and are under investigation for a wide range of other conditions, from kidney and heart disease to addiction to dementia

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Individuals who are pregnant, planning on becoming pregnant, or breastfeeding, have a history of severe kidney or liver disease, pancreatitis, gallbladder disease, diabetic retinopathy, thyroid C-cell tumors, or certain types of cancer, or those who have had severe hypersensitivity to semaglutide or any of its components may not be suitable for this treatment

(2017) Reactive oxygen species and cancer paradox: to promote or to suppress

Without hormonal stability, dose adjustments may produce inconsistent results