In the randomized double-blind controlled study STEP-1 (Research Study Investigating How Well Semaglutide Works in People Suffering From Overweight or Obesity), the treatment of adults with obesity once-weekly with semaglutide at a dose of 2.4 mg resulted in a mean reduction in body weight of approximately 15%, compared to 3% in the control group [7]
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Gamma-glutamyl transferase (GGT), a key liver function biomarker, indicates liver disease and chronic conditions like diabetes and cancer
Weekly or biweekly injections could be appropriate, but the schedule can depend on many factors
After 3 months of treatment, serum vitamin B12 levels were increased in all 9 patients in whom it was measured (mean increase of 117.4 pg/mL
Obesity 2020, 28(6):10501061