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Diabetes Care 2020;43:e108-10
Starting and stopping Retatrutide can cause side effects to recur as your body re-adjusts
Most peptide-based medicines are not orally bioavailable, as digestive enzymes would break them down before they reach the bloodstream (though exceptions exist, such as oral semaglutide)
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Stick to your titration schedule Your doctor will initiate semaglutide at a low dose (0.25 mg) and gradually increase it every 4 weeks to minimize side effects and help your body adjust to the medication
Warren, M
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