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doi: 10.2337/dc10-0612 12 HenryRRMurrayAVMarmolejoMHHennickenDPtaszynskaAListJF

PLoS ONE 16 , e0260797 (2021)

However, GSH has an overall negative charge at physiological pH, and mitochondria also exhibit an enormous negative membrane potential [57, 58]

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Collectively, abnormal expression or activity of these mitochondrial transporters in tumor cells can affect mitochondrial function, metabolic reprogramming, and oxidative stress, impacting tumor expansion and progression

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