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Gradual Introduction: Start with lower concentrations (e.g., 0.05% to 1%) and less frequent application (e.g., every other day) to allow the skin to acclimate, especially for sensitive skin types

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However, DR-10,624, a GLP-1/GCG/fibroblast growth factor 21 (FGF-21) triple agonist is under investigation for individuals with severe hypertriglyceridemia (not limited to individuals with obesity