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Important: maintain pH above 5.0, as the copper ion dissociates in acidic conditions

*Correspondence: Daniel Elas, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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This route can achieve very high purity and a welldefined product profile, making it attractive for laboratory use, specialty pharmaceutical intermediates, and situations where precise control of impurities is critical, though at a higher production cost and smaller scale

It can also obscure the fact that there is no validated human use, dose, safety profile or approved indication

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