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RomeroMToralMGmez-GuzmnMJimnezRGalindoPSnchezMet alAntihypertensive effects of oleuropein-enriched olive leaf extract in spontaneously hypertensive rats
The May 2026 Nature study showing central amygdala activation by oral GLP-1 drugs provides a neurobiological explanation for these observations
All four cases of MTC exhibited cytoplasmic GLP-1R expression
However, it is important to note that peptides administered subcutaneously may undergo local catabolism in the SubQ compartment before reaching systemic circulation, which can impact their bioavailability and therapeutic efficacy
Human evidence: Relies on observational models
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