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Akkermansia muciniphila ) as well as Firmicutes ( Clostridiales , Oscillospiraceae )

The ultimate choice must be made in consultation with an expert physician who can interpret the latest data and integrate the drug into a broader program focused on precision metabolic medicine and longevity

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As a synthetic analog of its endogenous exendin-4, compared with exendin-4, LIXI deleted one proline and added six lysine residues, which increased its binding affinity with the GLP-1R by four times and increased its circulating half-life (58, 59)