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However, the medication's gastrointestinal effectsparticularly nausea, vomiting, and diarrheacan lead to dehydration and prerenal acute kidney injury if fluid intake is inadequate
Additional warnings include inflammation of the pancreas (pancreatitis), severe gastrointestinal reactions, acute kidney injury, low blood sugar (hypoglycemia), serious allergic reactions, diabetic retinopathy complications in patients with type 2 diabetes, and acute gallbladder disease
Lilly redesignated the compound as LY3502970 and later assigned the international nonproprietary name orforglipron
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10.1194/jlr.M300462-JLR200