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Like GLP-1, GIP helps regulate insulin and reduce appetite, but it also boosts fat metabolism and improves insulin sensitivity
See Figure 2 for a schematic representation of the main processes driving BBB disruption in these diseases
The intracerebroventricular (ICV) injection of the DEETGE-Cal-Tat peptide showed an increased expression of Nrf2- regulated genes and marked neuroprotective and cognitive-preserving effects in mice subjected to brain injury [301]
The compound reaches distant structures joints, tendons, muscle, brain at meaningful concentrations
B.Garrido-MartnezM.et al (2019)
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