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They are generating mice in which the protein SPHKAP can be specifically deleted from -cells, allowing them to examine how disrupting this signalling hub affects pancreatic function and GLP-1R signalling
However, little is known about the kinetics of the GLP-1 metabolite in mice
An overview of rational design of mRNA-based therapeutics and vaccines
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Ferreira ST, Clarke JR, Bomfim TR, De Felice FG
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