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Supplementation of 500 mg/d for 4 weeks downregulated the HPA axis, altered the typical pattern of ACTH and cortisol change, and reduced immune response activation in Mg-supplemented rugby players (Dmitrainovi 2016) Omega-3 Fatty Acids 1 to 2 g/d (Jahangard 2019, Kiecolt-Glaser 2011) Daily 1,000 mg omega-3 supplementation for 8 consecutive weeks positively influenced psychological and physiological markers of occupational burnout, including lowering morning cortisol (Jahangard 2019)

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Kononen, J., Honkaniemi, J., Gustafsson, J

Individual researchers rarely have access to HPLC verification, which is why strict cold-chain adherence is non-negotiable