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AHK-Cu (Ala-His-Lys copper complex) engages copper-dependent signaling pathways, acting as a copper-binding tripeptide that modulates extracellular matrix remodeling enzyme activity

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Since changes in bone tissue manifest as fractures with a long delay, this may hint at more pronounced slow-acting effects on bone of the two drugs, although imbalances in confounding factors between the groups may also arise as time passes

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