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The sample sizes are small, but the pattern is unmistakable

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Furthermore, GLP-1RAs alleviate inflammation by decreasing the levels of TNF-, IFN-, MMP-9 and other pro-atherogenic factors, thereby slowing the progression of atherosclerosis 44

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In contrast with the consistent finding of reduced abundance of butyrate-producing bacteria in T2D, different studies report extensive variation for the levels of butyrate in feces and/or blood of individuals with T2D compared to controls

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