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B12 plays a role in cellular energy metabolism, and some providers argue that ensuring optimal B12 levels helps mitigate treatment-related fatigue, particularly in patients who were subclinically deficient before starting
Enhances Muscle Preservation By inhibiting the enzyme nicotinamide N-methyltransferase (NNMT), it enhances cellular energy expenditure, encouraging the body to utilize stored fat as an energy source rather than breaking down muscle tissue
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Hydroxocobalamin is a long-acting B12 used for deficiency with less frequent dosing