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It is a convergent architecture: a peptide that modulates NO bioavailability at the eNOS level, drives VEGF-mediated angiogenesis at the transcriptional level, protects cell-matrix adhesion through FAK-paxillin signaling, and attenuates local inflammatory cascades through apparent NF-B modulation all of this through a structurally stable, proteolysis-resistant scaffold that delivers these signals intact to target tissues
Potential role of natural bioactive peptides for development of cosmeceutical skin products Type of study: Number of citations: 108 Year: 2019 Authors: J
The whole human ledger is compartment-directed dosing: intra-articular into the knee, intravesical into the bladder wall, rectal enema onto colonic mucosa
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