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mGlu2 receptors regulate pain transmission by acting as a brake in the spinal nociceptive synapse (Fig

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Most side effects are gastrointestinal in nature because the medication primarily interacts with the gut

The glucagon component specifically increases energy expenditure and fat mobilization

Although PIONEER 6 only showed an insignificant reduction of MACE, subcategory analysis demonstrated significant improvement in all-cause mortality [1.4% vs