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Obesity is a well-known risk factor for acid reflux, and the significant weight loss achieved by some patients on higher doses of semaglutide might ultimately lead to a decrease in reflux symptoms over time

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Side effect risk depends on your health history, dosage, treatment plan, and provider monitoring

Semaglutide has also been linked in some early clinical trials to a temporary worsening of diabetic retinopathy, due to the rapid drop in blood sugar that can stress the retina blood vessels in those with pre-existing eye disease