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Therefore, 30 patients diagnosed with HF were given 1000 mg NR twice a day for 12 weeks, which increased whole blood NAD + levels and corresponded with higher peripheral blood mononuclear cells (PMBCs) mitochondrial respiration and reduced ROS production 318

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The COMT enzyme requires a constant supply of methyl groupsprovided by the B12-dependent methylation cycleto function

You also get vitamin B12 in eggs, dairy, and foods fortified with this nutrient

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