Suitability is confirmed at consultation before treatment
Some patients may benefit from very low-calorie diets (800 kcal/day) under medical supervision, particularly those with type 2 diabetes or significant obesity-related complications, as outlined in NICE CG189
Osteoarthritis and joint pain
The choice between medications should rest primarily on efficacy data, tolerability, availability, and cost rather than the B12 inclusion, which is valuable in both formulations
Semaglutide and liraglutide have received FDA approval specifically for chronic weight management in adults with obesity or overweight with at least one weight-related comorbidity
As interest in performance-related peptides grows, education-driven, compliance-focused research remains essential