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Curcumin modulates critical pathways such as NF-B and downregulates IL-6 and TNF- signaling, leading to improvements in both glucose metabolism and depressive symptoms (Sarmiento-Ortega et al., 2025
bitter melon and tung tree) 26 and was previously shown to suppress the growth of breast cancer cells in a manner reversible by antioxidants 27
Both preclinical and clinical studies have demonstrated that GLP-1s modulate the gut microbiota composition by delaying gastric emptying and altering luminal glucose (12)
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