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Third, we used mean and SDs for pooling VAS

Monotherapy Use of Semaglutide in Patients with Type 2 Diabetes Mellitus In a 30-week double-blind trial (NCT02054897), 388 patients with type 2 diabetes mellitus inadequately controlled with diet and exercise were randomized to semaglutide 0.5 mg or semaglutide 1 mg once weekly or placebo

These were landmark numbers that established tirzepatide as the most effective approved weight loss medication at the time of its launch

33,34 Because acute kidney injury is associated with accelerated progression to chronic kidney disease and increased cardiovascular morbidity, careful evaluation of the renal safety of contemporary glucose-lowering and weight management therapies is essential

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